Dexmedetomidine and Propofol in the Treatment of Emergence Agitation

Phase 0 Unknown 120 enrolled RenJi Hospital

RandomizedParallel-groupTriple-blindTreatment

Summary

1. This clinical research aims to compare the effects of dexmedetomidine and propofol on the treatment of emergence agitation in adult patients after general anesthesia. 2. Half of participants will receive dexmedetomidine while the other half will receive propofol when emergence agitation happens.

Timeline

Start: 2019-11-01
Primary completion: 2021-08-30
Completion: 2021-08-30

Publications

Feng Z, Shi X, Yan X, Zhu Y, Gu J, Zhu H, Yu W, Zhang S. Comparing the effects of dexmedetomidine versus propofol on the treatment of emergence agitation in adult patients after general anesthesia: study protocol for a randomized, superiority, controlled trial (DP-TEA Trial). Trials. 2021 Nov 16;22(1):811. doi: 10.1186/s13063-021-05743-2.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Dexmedetomidine	Other / unclassified	0.7 ug/kg	—
Comparator	Propofol	Small molecule	0.5 mg/kg	—

Indications

No indication recorded.