drugset / Trial / NCT07241351

Dexmedetomidine as an Adjunct to Fentanyl for Term Neonates on Mechanical Ventilation

NCT07241351

Phase 2/3 Completed 40 enrolled Ain Shams University
RandomizedParallel-groupTriple-blindTreatment

Summary

Despite well conducted studies on pain management in mechanically ventilated neonates, there is still a need for exploration of appropriate and accurate pharmacological management strategies for this ongoing pain, and assessment of the clinical impact of the used drugs for analgesia and sedation. In the current study, the aim was to reduce fentanyl doses on mechanical ventilated neonates after adding Dexmedetomidine

Timeline

Start
2024-03-01
Primary completion
2024-11-01
Completion
2025-07-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexmedetomidine Other / unclassified 0.3 ug/kg Intravenous
Subject Dexmedetomidine Other / unclassified 0.5 ug/kg Intravenous
Comparator Fentanyl Other / unclassified 0.5 ug/kg
Comparator Fentanyl Other / unclassified 1 ug/kg

Indications

No indication recorded.