drugset / Trial / NCT00826553

How Your Patients' Non-REM Sleep Changes On Sedatives in the Intensive Care Units

NCT00826553

Phase 1 Terminated 6 enrolled Vanderbilt University Medical Center
RandomizedParallel-groupSingle-blindOther

Summary

The purpose of this study is to study the effect of two standard of care sedative medications on sleep stages and total sleep time. The investigators hypothesize that the α2 agonist, dexmedetomidine, will improve sleep quality by increasing N2 and N3 sleep as well as total sleep time when compared to GABA agonists.

Timeline

Start
2009-01
Primary completion
2013-12
Completion
2013-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexmedetomidine Other / unclassified
Subject Lorazepam Small molecule
Subject Midazolam Small molecule
Subject Propofol Small molecule