Articaine vs Dexmedetomidine Supplemented Articaine

Phase 0 Completed 50 enrolled Ain Shams University

RandomizedParallel-groupTriple-blindTreatment

Summary

The aim of this study to test efficacy of adding dexmedetomidine to articaine on sensory, motor and duration of analgesia during hemodialysis fistula creation under ultrasound guided supraclavicular block

Timeline

Start: 2019-06-01
Primary completion: 2019-10-01
Completion: 2019-11-01

Outcome

Met primary endpoint

paper Longer sensory block duration was in Group AD (230-260 min) than in Group A (172-185 min) with P < 0.001. PMID 33487824 ↗

paper In addition, motor block duration was significantly longer in Group AD than in Group A PMID 33487824 ↗

Publications

Armanious SH, Abdelhameed GA. Articaine and Dexmedetomidine - Supplemented Articaine for Arteriovenous Fistula Creation under Ultrasound-guided Supraclavicular Block. Anesth Essays Res. 2020 Apr-Jun;14(2):248-252. doi: 10.4103/aer.AER_147_19. Epub 2020 Oct 12.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Articaine	Other / unclassified	2 %	Other
Subject	Articaine	Other / unclassified	40 ml	Other
Subject	Dexmedetomidine	Other / unclassified	1 ug/kg	Other