drugset / Trial / NCT01083797
Sedation to Electroencephalography With Dexmedetomidine or Chloral Hydrate
Phase 3
Completed
25 enrolled
Federal University of Minas Gerais
Santa Casa de Misericórdia de Belo Horizonte · collab
NaSingle-groupSingle-blindTreatment
Summary
This study evaluates the use of dexmedetomidine or chloral hydrate for sedation during electroencephalography in patients with neurological disorders. The hypothesis is that this drugs provides similar changes in EEG pattern.
Timeline
- Start
- 2009-12
- Primary completion
- 2013-03
- Completion
- 2013-10
Publications
- Background Lubisch N, Roskos R, Berkenbosch JW. Dexmedetomidine for procedural sedation in children with autism and other behavior disorders. Pediatr Neurol. 2009 Aug;41(2):88-94. doi: 10.1016/j.pediatrneurol.2009.02.006.
- Background Huupponen E, Maksimow A, Lapinlampi P, Sarkela M, Saastamoinen A, Snapir A, Scheinin H, Scheinin M, Merilainen P, Himanen SL, Jaaskelainen S. Electroencephalogram spindle activity during dexmedetomidine sedation and physiological sleep. Acta Anaesthesiol Scand. 2008 Feb;52(2):289-94. doi: 10.1111/j.1399-6576.2007.01537.x. Epub 2007 Nov 14.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Chloral Hydrate | Small molecule | 50 mg/kg | — |
| Subject | Dexmedetomidine | Other / unclassified | 0.2 ug/kg | — |
| Subject | Dexmedetomidine | Other / unclassified | 0.7 ug/kg | — |