drugset / Trial / NCT07167316

The Role of the LC-NA System in Experimental Sleep Fragmentation

NCT07167316

Phase 1 Recruiting 42 enrolled Hans-Peter Landolt Wellcome Trust · collab
RandomizedCrossoverDouble-blindBasic science

Summary

Sleep-wake regulation affects every person's life, yet the molecular mechanisms underlying these processes remain poorly understood. In particular, the microstructure of sleep has not been sufficiently studied to explain how sleep produces a feeling of restoration the following morning. Stress also plays a significant role in sleep regulation. This study aims to investigate the role of norepinephrine in these processes.

Timeline

Start
2026-05-21
Primary completion
2026-12-01
Completion
2027-10-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexmedetomidine Other / unclassified 64 ug Other
Subject Dexmedetomidine Other / unclassified 96 ug Other

Indications

No indication recorded.