drugset / Trial / NCT02515890

Memory Modulation by Pain During Anesthesia

NCT02515890

RandomizedCrossoverSingle-blindBasic science

Summary

The purpose of this study is to determine the effects of pain on facilitating long-term auditory memory in the presence and absence of distinct intravenous anesthetics. The ability to identify previously presented words from a list assessed the degree of memory formation. In a subset of subjects, functional magnetic resonance imaging was used to identify the neural correlates of memory inhibition or facilitation by the combination of pain and anesthetic used.

Timeline

Start
2015-11-19
Primary completion
2018-12-12
Completion
2018-12-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexmedetomidine Other / unclassified Intravenous
Subject Ketamine Small molecule Intravenous
Subject Midazolam Small molecule Intravenous

Indications