drugset / Trial / NCT02515890
Memory Modulation by Pain During Anesthesia
Phase 1
Completed
32 enrolled
University of Pittsburgh
Foundation for Anesthesia Education and Research · collab
RandomizedCrossoverSingle-blindBasic science
Summary
The purpose of this study is to determine the effects of pain on facilitating long-term auditory memory in the presence and absence of distinct intravenous anesthetics. The ability to identify previously presented words from a list assessed the degree of memory formation. In a subset of subjects, functional magnetic resonance imaging was used to identify the neural correlates of memory inhibition or facilitation by the combination of pain and anesthetic used.
Timeline
- Start
- 2015-11-19
- Primary completion
- 2018-12-12
- Completion
- 2018-12-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexmedetomidine | Other / unclassified | — | Intravenous |
| Subject | Ketamine | Small molecule | — | Intravenous |
| Subject | Midazolam | Small molecule | — | Intravenous |