drugset / Trial / NCT01606852
Testing the Feasibility of Patient Controlled Sedation for Ventilated ICU Patients
Phase 1/2
Completed
15 enrolled
University of Minnesota
Hospira, now a wholly owned subsidiary of Pfizer · collabNational Institute of Nursing Research (NINR) · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
Mechanical ventilation (MV) is the most frequently used life-support modality in intensive care units (ICUs). To reduce anxiety, stress and promote tolerance of MV, nurses frequently administer a variety of sedative medications to their patients based on subjective observations. The investigators hypothesize that patient-controlled sedation, compared to clinician-directed sedation, will decrease sedative exposure while decreasing patient anxiety during the episode of mechanical ventilation.
Timeline
- Start
- 2013-03
- Primary completion
- 2014-07
- Completion
- 2015-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexmedetomidine | Other / unclassified | 0.2 ug/kg | Intravenous |
| Subject | Dexmedetomidine | Other / unclassified | 0.7 ug/kg | Intravenous |