drugset / Trial / NCT01606852

Testing the Feasibility of Patient Controlled Sedation for Ventilated ICU Patients

NCT01606852

RandomizedParallel-groupOpen-labelTreatment

Summary

Mechanical ventilation (MV) is the most frequently used life-support modality in intensive care units (ICUs). To reduce anxiety, stress and promote tolerance of MV, nurses frequently administer a variety of sedative medications to their patients based on subjective observations. The investigators hypothesize that patient-controlled sedation, compared to clinician-directed sedation, will decrease sedative exposure while decreasing patient anxiety during the episode of mechanical ventilation.

Timeline

Start
2013-03
Primary completion
2014-07
Completion
2015-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexmedetomidine Other / unclassified 0.2 ug/kg Intravenous
Subject Dexmedetomidine Other / unclassified 0.7 ug/kg Intravenous