drugset / Trial / NCT05615727
Intranasal Dexmedetomidine and Zolpidem for Treatment of Primary Insomnia
RandomizedCrossoverDouble-blindTreatment
Summary
Insomnia is a significant public health burden, increasing work absenteeism and health care costs in a large proportion of the population. It causes altered cognition, emotional disturbances, and reduced quality of life. The purpose of this study is to determine whether the sleep promoting effect of dexmedetomidine is superior to the conventional sleep promoting drug, zolpidem. The main outcome of this study is to measure the time taken to fall asleep. Investigators will also look at incidences of wakening after sleep onset, sleep quality and wake time during sleep.
Timeline
- Start
- 2022-09-01
- Primary completion
- 2023-09
- Completion
- 2024-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexmedetomidine | Other / unclassified | 2 ug/kg | Intranasal |
| Comparator | Zolpidem | Small molecule | 10 mg | — |