drugset / Trial / NCT05615727

Intranasal Dexmedetomidine and Zolpidem for Treatment of Primary Insomnia

NCT05615727

Phase 3 Unknown 20 enrolled The University of Hong Kong
RandomizedCrossoverDouble-blindTreatment

Summary

Insomnia is a significant public health burden, increasing work absenteeism and health care costs in a large proportion of the population. It causes altered cognition, emotional disturbances, and reduced quality of life. The purpose of this study is to determine whether the sleep promoting effect of dexmedetomidine is superior to the conventional sleep promoting drug, zolpidem. The main outcome of this study is to measure the time taken to fall asleep. Investigators will also look at incidences of wakening after sleep onset, sleep quality and wake time during sleep.

Timeline

Start
2022-09-01
Primary completion
2023-09
Completion
2024-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexmedetomidine Other / unclassified 2 ug/kg Intranasal
Comparator Zolpidem Small molecule 10 mg

Indications