drugset / Trial / NCT01565590
Effects of Dexmedetomidine on Inflammatory Cytokines in Patients With Aneurysmal Subarachnoid Hemorrhage
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this research is to compare patients with aneurysmal subarachnoid hemorrhage on dexmedetomidine compared to propofol to assess if one group has decreased inflammation. The investigators hypothesis is that the group assigned to receive dexmedetomidine will have a more profound decrease in markers of inflammation over time.
Timeline
- Start
- 2012-02
- Primary completion
- 2015-07
- Completion
- 2015-07
Outcome
Outcome not reported
Stopped (Enrollment): “Slow enrollment along with new competing studies, investigators decided to stop study”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexmedetomidine | Other / unclassified | 0.2 ug/kg | — |
| Subject | Dexmedetomidine | Other / unclassified | 1.5 ug/kg | — |
| Comparator | Propofol | Small molecule | 5 ug/kg | — |
| Comparator | Propofol | Small molecule | 80 ug/kg | — |