drugset / Trial / NCT06756178

Effect of Remimazolam Versus Dexmedetomidine on the Incidence of Delirium After Elective Cardiac Surgery with Cardiopulmonary Bypass: a Prospective Randomized Controlled Trial

NCT06756178

Phase 0 Not yet recruiting 111 enrolled Assiut University
RandomizedParallel-groupDouble-blindPrevention

Summary

The study aims to improve the post-open heart surgery lifestyle and overall experience, as well as assess the incidence of delirium using Remimazolam and Dexmedetomidine.

Timeline

Start
2025-01-10
Primary completion
2026-11-01
Completion
2027-11-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexmedetomidine Other / unclassified 0.2 ug/kg
Subject Dexmedetomidine Other / unclassified 0.7 ug/kg
Comparator Propofol Small molecule 0.3 mg/kg Intravenous
Comparator Propofol Small molecule 0.5 mg/kg Intravenous
Subject Remimazolam Small molecule 0.2 mg/kg Intravenous
Subject Remimazolam Small molecule 0.3 mg/kg Intravenous

Indications