drugset / Trial / NCT01188551
Dexmedetomidine Versus Fentanyl Following Pressure Equalization Tube Placement
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This is a study to compare intranasal dexmedetomidine to intranasal fentanyl following anesthesia induction in patients undergoing myringotomy and placement of pressure equalization (PE) tubes in providing analgesia and smoothing emergence from general anesthesia.
Timeline
- Start
- 2011-01
- Primary completion
- 2012-04
- Completion
- 2012-04
Publications
- Background Tobias JD. Dexmedetomidine: applications in pediatric critical care and pediatric anesthesiology. Pediatr Crit Care Med. 2007 Mar;8(2):115-31. doi: 10.1097/01.PCC.0000257100.31779.41.
- Background Yuen VM, Irwin MG, Hui TW, Yuen MK, Lee LH. A double-blind, crossover assessment of the sedative and analgesic effects of intranasal dexmedetomidine. Anesth Analg. 2007 Aug;105(2):374-80. doi: 10.1213/01.ane.0000269488.06546.7c.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexmedetomidine | Other / unclassified | 1 ug/kg | Intranasal |
| Comparator | Fentanyl | Other / unclassified | 2 ug/kg | Intranasal |
| Background | Midazolam | Small molecule | 0.5 mg/kg | Oral |