drugset / Trial / NCT06935292

Oral Melatonin VS Nebulized Dexmedetomidine Premedication on Attenuation of Hemodynamic Response to Direct Laryngoscopy and Tracheal Intubation in Hypertensive Patients

NCT06935292

Phase 2/3 Not yet recruiting 70 enrolled Tanta University
RandomizedParallel-groupDouble-blindPrevention

Summary

The aim of this study is to compare the efficacy of oral melatonin versus nebulized dexmedetomidine in attenuating the hemodynamic response to direct laryngoscopy and endotracheal intubation in controlled hypertensive patients prepared for general anesthesia

Timeline

Start
2025-04
Primary completion
2026-04
Completion
2026-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexmedetomidine Other / unclassified 1 ug/kg Inhaled
Subject Melatonin Small molecule 5 mg Oral

Indications

No indication recorded.