A Comparative Study of Oral Gabapentin, Oral Alprazolam and Intravenous Dexmedetomidine on Perioperative Anxiety and Pain During Posterior Segment Eye Surgery Under Peribulbar Block : a Randomized, Double-blind Study.

Phase 1 Unknown 45 enrolled Ehab Tarek Fahmy

RandomizedParallel-groupDouble-blindTreatment

Summary

We hypothesized that gabapentin when given orally as a premedication in patients who perform posterior segment eye surgery under peribulbar block would provide adequate anxiolysis and arousable sedation as alprazolam and dexmedetomidine with minimal side effects .

Timeline

Start: 2020-12-01
Primary completion: 2021-06-01
Completion: 2021-08-01

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Alprazolam	Small molecule	0.25 mg	Oral
Subject	Dexmedetomidine	Other / unclassified	0.25 ug/kg	Intravenous
Subject	Gabapentin	Small molecule	600 mg	Oral

Indications

No indication recorded.