drugset / Trial / NCT01084473
Effect of Dexmedetomidine on Gastric Emptying and Gastrointestinal Transit
RandomizedCrossoverSingle-blind
Summary
The aim of the study is to determine the effect of dexmedetomidine infusion on gastric emptying and oro-caecal transit time in healthy volunteers, judged by measuring plasma paracetamol concentrations after paracetamol ingestion and pulmonary hydrogen measurement technique after lactulose ingestion. The effects of dexmedetomidine will be compared to the effects of morphine and placebo.
Timeline
- Start
- 2010-03
- Primary completion
- 2010-06
- Completion
- 2010-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexmedetomidine | Other / unclassified | 0.7 ug/kg | — |
| Comparator | Morphine | Other / unclassified | 0.1 mg/kg | — |
Indications
No indication recorded.