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drugset / Trial / NCT03668951

Pharmacokinetic Study of Dexmedetomidine After Intra-Nasal and Buccal Dosing in Children

NCT03668951 ↗

Phase 1 Completed 18 enrolled Children's Hospital Medical Center, Cincinnati
Non-randomizedParallel-groupOpen-labelBasic science

Summary

This research study is a continuation of a previous DEX PK study. It is examining the absorption of Dexmedetomidine (DEX) in the blood when given orally and as a nasal spray. This study will help us determine the best dosing amount for children undergoing sedation or anesthesia with DEX.

Timeline

Start
2018-08-20
Primary completion
2022-05-03
Completion
2022-05-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexmedetomidine Other / unclassified 2 ug/kg Other
Subject Dexmedetomidine Other / unclassified 3 ug/kg Other
Subject Dexmedetomidine Other / unclassified 4 ug/kg Other

Indications

heart disorder