drugset / Trial / NCT02752477
Efficacy of Opioid-free Anesthesia in Reducing Postoperative Pain in Chronic Pain Patients Undergoing Spinal Surgery
RandomizedParallel-groupSingle-blindTreatment
Summary
The objective of this trial is to determine whether an opioid-free general anesthetic (OFA) technique utilizing ketamine, dexmedetomidine, and lidocaine infusions can help reduce postoperative pain in opiate-dependent chronic pain patients (CPPs) undergoing spine surgery when compared with traditional opioid-containing techniques. It is expected that this OFA regimen will have a measurable reduction on postoperative opioid consumption and pain scores in CPPs.
Timeline
- Start
- 2016-08-02
- Primary completion
- 2020-09
- Completion
- 2020-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexmedetomidine | Other / unclassified | — | — |
| Comparator | Fentanyl | Other / unclassified | — | — |
| Subject | Ketamine | Small molecule | — | — |
| Subject | Lidocaine | Other / unclassified | — | — |
| Comparator | Remifentanil | Small molecule | — | — |
| Comparator | Sufentanil | Other / unclassified | — | — |