drugset / Trial / NCT02836431

Pharmacokinetic Study of Dexmedetomidine After Intra-nasal Dosing in Children

NCT02836431

Phase 1 Completed 18 enrolled Children's Hospital Medical Center, Cincinnati
Non-randomizedParallel-groupOpen-labelBasic science

Summary

This research study is examining the absorption of the sedative dexmedetomidine (DEX) in the blood when given by nasal spray. The study will help us determine the best dosing amount for children undergoing sedation or anesthesia with DEX.

Timeline

Start
2016-01
Primary completion
2017-12
Completion
2018-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexmedetomidine Other / unclassified 1 ug/kg Intranasal
Subject Dexmedetomidine Other / unclassified 2 ug/kg Intranasal

Indications