drugset / Trial / NCT07081581
Analgesic Effect of Serratus Plane Block With Adjuvant Agents in Breast Cancer Surgery
Phase 2
Completed
75 enrolled
Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
RandomizedParallel-groupDouble-blindTreatment
Summary
Pain after breast surgery has been described as moderate to severe in intensity and, if inadequately treated, increases postoperative morbidity, hospital cost, and the incidence of persistent postoperative pain. Serratus anterior plane block is an interfascial injection technique for analgesia of the chest wall. The aim of this study was to investigate the effect of magnesium and dexmedetomidine as adjuvant agents on postoperative analgesia in serratus anterior plane block in patients undergoing modified radical mastectomy.
Timeline
- Start
- 2022-08-01
- Primary completion
- 2023-02-01
- Completion
- 2023-03-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexmedetomidine | Other / unclassified | 1 ug/kg | Other |
| Subject | Magnesium Sulfate | Other / unclassified | 500 mg | Other |
| Background | Bupivacaine | Other / unclassified | 0.25 % | Other |
| Background | Bupivacaine | Other / unclassified | 30 ml | Other |