drugset / Trial / NCT07538284

MInimizing Delirium With Nasal Dexmedetomidine-InducEd Sleep (MIDDIES)

NCT07538284

Phase 2/3 Not yet recruiting 400 enrolled Sixth Affiliated Hospital, Sun Yat-sen University
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study aims to determine whether, compared with placebo, the nighttime self-administration of a nasal dexmedetomidine is effective at inducing sleep and preventing postoperative delirium in high-risk patients.

Timeline

Start
2026-05-01
Primary completion
2026-12-31
Completion
2027-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexmedetomidine Other / unclassified 100 ug Intranasal

Indications