drugset / Trial / NCT04276545

Dexmedetomidine Improves the Surgical Field and Postoperative Recovery of Nasal Endoscopic Surgery

NCT04276545

Phase 3 Completed 118 enrolled Eye & ENT Hospital of Fudan University
RandomizedParallel-groupTriple-blindSupportive care

Summary

Studies showed dexmedetomidine (DEX) could improve surgical field, but the effect for functional nasal endoscopic surgery (FESS) was unclear. The investigators explored IV administration of a single loading dose DEX (0.5μg/kg) for FESS, and IV administration of midazolam (0.05mg/kg) as a control with comparision of surgical field, haemodynamics, ventilation parameters and recovery.

Timeline

Start
2018-01-01
Primary completion
2020-03-10
Completion
2020-03-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexmedetomidine Other / unclassified 0.5 ug/kg Intravenous
Subject Midazolam Small molecule 0.05 mg/kg Intravenous

Indications