drugset / Trial / NCT07832214
Effects of Dexmedetomidine Combined With Lidocaine Topical Administration on Cough Reflex During Extubation in Thyroidectomy Patient.
RandomizedParallel-groupQuadruple-blindHealth-services research
Summary
Study Hypothesis: The combination of dexmedetomidine and lidocaine administered as laryngopharyngeal topical spray provides superior suppression of extubation cough reflex compared to lidocaine alone or placebo, without compromising recovery or increasing adverse events
Timeline
- Start
- 2026-07-01
- Primary completion
- 2026-11
- Completion
- 2026-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexmedetomidine | Other / unclassified | 1 ug/kg | Topical |
| Comparator | Lidocaine | Other / unclassified | 2 % | Topical |
Indications
No indication recorded.