Drugs / AZD2811
last change Apr 2026 re-read 3 minutes ago

AZD2811

targets AURKB via inhibition

Developed for
small cell lung carcinoma · acute myeloid leukemia · neoplasm
Investigated by
AstraZeneca · Samsung Medical Center · Se-Hoon Lee

Trials 5

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT03217838 Jul 2017 → Mar 2021 acute myeloid leukemia AstraZeneca Terminated No outcome recorded Stop: Business
Phase 1 NCT02579226 Oct 2015 → Feb 2020 neoplasm AstraZeneca Completed No outcome recorded
Phase 23 trials
Phase 2 NCT04745689 Feb 2021 → Jun 2022 overdue small cell lung carcinoma AstraZeneca Active not recruiting No outcome recorded
Phase 2 NCT04525391 Sep 2020 → Jan 2022 small cell lung carcinoma Se-Hoon Lee Terminated No outcome recorded
Phase 2 NCT03366675 Dec 2017 → Oct 2018 small cell lung carcinoma Samsung Medical Center Terminated No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as AZD2811 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04525391 ↗
4

NCT03217838 ↗

NCT02579226 ↗

NCT03366675 ↗

NCT04745689 ↗

Action Inhibit “AZD2811 is an AURKB inhibitor” PMID 41933194 ↗ Apr 2026
Route Intravenous “AZD2811 was administered in 12 dose-escalation cohorts (2-h intravenous infusion; 15‒600 mg; 21-/28-day cycles)” PMID 36871042 ↗ Mar 2023
Target AURKB “AZD2811 is an AURKB inhibitor” PMID 41933194 ↗ Apr 2026