drugset / Trial / NCT04745689

Study of AZD2811 + Durvalumab in ES-SCLC

NCT04745689 ↗

Phase 2 Active not recruiting 31 enrolled AstraZeneca
Non-randomizedSingle-groupOpen-labelTreatment

Summary

A Phase II Multicenter, Open-Label, Single Arm Study to Determine the Efficacy, Safety and Tolerability of AZD2811 and Durvalumab Combination as Maintenance Therapy After Induction with Platinum-Based Chemotherapy Combined with Durvalumab, for the First-Line Treatment of Patients with Extensive Stage Small-Cell Lung Cancer.

Timeline

Start
2021-02-23
Primary completion
2022-06-18
Completion
2026-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject AZD2811 Unknown — Intravenous
Subject Durvalumab Monoclonal antibody — Intravenous
Background Carboplatin Small molecule — Intravenous
Background Cisplatin Other / unclassified — Intravenous
Background Etoposide Small molecule — Intravenous