Drugs / ChAdOx1 nCoV-19 vaccine
last change Dec 2023 re-read 9 days ago

ChAdOx1 nCoV-19 vaccine

also known as AZD1222

Vaccine

Developed for
COVID-19
Investigated by
Centro de Pesquisas René Rachou · Federal University of Espirito Santo

Trials 1

202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT05133609 Jan 2021 → Aug 2022 COVID-19 Federal University of Espirito Santo Unknown No outcome recorded
Comparator or background therapy1 trial
Phase 1/2 NCT04730895 Comparator Jul → Sep 2021 — Kafrelsheikh University Unknown No outcome recorded

News releases announcing trial results or a regulatory action · 2

DateIssuerRelease
2021-07-23 AstraZeneca Results Vaxzevria is highly effective after one dose against severe disease or hospitalisation caused by Beta and Delta variants of concern astrazeneca.com ↗
The vaccine also showed a high level of effectiveness against the Delta (B.617.2, ‘Indian’) and Alpha (B.1.1.7, ‘Kent’) variants with an 87% and 90% reduction of hospitalisations or deaths respectively.
2021-05-21 AstraZeneca Regulatory AstraZeneca COVID-19 vaccine Vaxzevria authorised for emergency use in Japan astrazeneca.com ↗
AstraZeneca’s COVID-19 vaccine, Vaxzevria (ChAdOx1-S [Recombinant]) , formerly AZD1222, has been granted a special approval for emergency use in Japan for active immunisation of individuals aged 18 years and older, to prevent COVID-19 caused by SARS-CoV-2.

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as ChAdOx1 nCoV-19 vaccine ClinicalTrials.gov intervention name — accepted as the source's own label NCT05133609 ↗
1

NCT04730895 ↗

Known as AZD1222 “ChAdOx1 nCoV-19 vaccine (AZD1222)” NCT05133609 ↗
Modality Vaccine “spike protein based vaccine such as ChAdOx1 nCoV-19 vaccine” NCT04730895 ↗