drugset / Trial / NCT05133609
COVID-19 VACCINE SAFETY AND EFFECTIVENESS
Phase 1/2
Unknown
550 enrolled
Federal University of Espirito Santo
Centro de Pesquisas René Rachou · collab
Non-randomizedSequentialOpen-labelPrevention
Summary
A longitudinal open-label study will include health professionals and patients with immune-mediated inflammatory diseases (IMID) who will receive the ChAdOx1 nCoV-19 vaccine (AZD1222), in a standard 3-dose schedule with an interval of 12 weeks (first-second dose) and 24 weeks (second-thrid dose), in the vaccination campaign against SARS-CoV-2 to assess the safety, efficacy and duration of the short- and long-term humoral and cellular immune response after vaccination for COVID-19 and compare the vaccine response between individuals who have or have not had previous SARS-Cov 2 infection.
Timeline
- Start
- 2021-01-15
- Primary completion
- 2022-08-01
- Completion
- 2023-12-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | ChAdOx1 nCoV-19 vaccine | Vaccine | — | — |