Drugs / FT576
last change Oct 2024 re-read 9 days ago

FT576

Cell therapy

Developed for
plasma cell myeloma
Investigated by
Fate Therapeutics

Trials 1

20222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05182073 Nov 2021 → Sep 2024 plasma cell myeloma Fate Therapeutics Completed No outcome recorded

News releases announcing trial results or a regulatory action · 2

DateIssuerRelease
2022-12-13 Fate Therapeutics Results Fate Therapeutics Features Multiple Novel Approaches to Eliminate Conditioning Chemotherapy for Off-the-shelf, iPSC-derived Cell Therapies at 2022 ASH Annual Meeting fatetherapeutics.com ↗
The translational findings suggest that following administration of daratumumab, CD38-null iNK cells may avoid rejection by activated host immune cells without requiring conditioning chemotherapy.
2022-12-10 Fate Therapeutics Results Fate Therapeutics Highlights iPSC-derived, Off-the-shelf CAR NK Cell Programs for Multiple Myeloma at 2022 ASH Annual Meeting fatetherapeutics.com ↗
Interim Phase 1 Data of FT576 BCMA-targeted Product Candidate Show Clinical Activity in Initial Single-dose Escalation Cohorts as Monotherapy and in Combination with Daratumumab

Evidence & citations 2 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as FT576 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05182073 ↗
Modality Cell therapy “FT576 comprises allogeneic natural killer (NK) cells” NCT05182073 ↗