drugset / Trial / NCT05182073

FT576 in Subjects With Multiple Myeloma

NCT05182073

Phase 1 Completed 31 enrolled Fate Therapeutics
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This is a Phase I dose-finding study of FT576 as monotherapy and in combination with the monoclonal antibody daratumumab in multiple myeloma (MM). The study will consist of a dose-escalation stage and an expansion stage.

Timeline

Start
2021-11-10
Primary completion
2024-09-20
Completion
2024-10-18

Drugs

EvaluationDrugModalityDoseRoute
Subject Daratumumab Monoclonal antibody
Subject FT576 Cell therapy
Background Bendamustine Small molecule
Background Cyclophosphamide Other / unclassified
Background Fludarabine Small molecule

Indications