Drugs / vedroprevir
last change Aug 2015 re-read 2 minutes ago

vedroprevir

also known as GS-9451 · VDV

Small molecule

Developed for
chronic hepatitis C virus infection
Investigated by
Gilead Sciences · National Institute of Allergy and Infectious Diseases (NIAID)

Trials 4 · a red edge is where a trial was stopped

2012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT02226549 Jul 2014 → Feb 2015 chronic hepatitis C virus infection Gilead Sciences Completed No outcome recorded
Phase 2 NCT01805882 Jan 2013 → Aug 2015 chronic hepatitis C virus infection National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 2 NCT01384383 Aug 2011 → Jun 2013 chronic hepatitis C virus infection Gilead Sciences Terminated No outcome recorded
Phase 2 NCT01371578 Jul 2011 → Mar 2013 chronic hepatitis C virus infection Gilead Sciences Completed No outcome recorded
Also used as a comparator or background therapy in 5 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT01435226 Comparator Sep 2011 → Jan 2013 chronic hepatitis C virus infection Gilead Sciences Completed No outcome recorded
Phase 2 NCT01434498 Comparator Sep 2011 → Jan 2013 chronic hepatitis C virus infection Gilead Sciences Completed No outcome recorded
Phase 2 NCT01356160 Comparator Jul 2011 → Jun 2013 chronic hepatitis C virus infection Gilead Sciences Completed No outcome recorded
Phase 2 NCT01353248 Comparator May 2011 → Oct 2012 chronic hepatitis C virus infection Gilead Sciences Completed No outcome recorded
Phase 2 NCT01271790 Comparator Oct 2010 → Jan 2013 chronic hepatitis C virus infection Gilead Sciences Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 10 sources stand behind the page.

FieldValueCited text
Known as vedroprevir “This study is to evaluate the antiviral efficacy, safety, and tolerability of combination therapy with ledipasvir/sofosbuvir (LDV/SOF) fixed-dose combination (FDC) +...” NCT02226549
Known as GS-9451 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01435226
7

NCT01805882

NCT01356160

NCT01434498

NCT01371578

NCT01271790

NCT01384383

NCT01353248

Known as VDV “This study is to evaluate the antiviral efficacy, safety, and tolerability of combination therapy with ledipasvir/sofosbuvir (LDV/SOF) fixed-dose combination (FDC) +...” NCT02226549
Action Inhibit “This is an open label study to assess the safety, tolerability, and efficacy of treatment with GS-7977 with GS-5885, alone or in combination with GS-9669 and/or GS-9451...” NCT01805882
Modality Small molecule CHEMBL2013174
Route Oral “GS-9451 tablet, 200 mg once daily (QD)” NCT01271790