drugset / Trial / NCT01434498

GS-5885, GS-9451, Tegobuvir and Ribavirin (RBV) in Interferon Ineligible or Intolerant Subjects With Chronic Genotype 1a or 1b Hepatitis C Virus (HCV) Infection

NCT01434498

Phase 2 Completed 163 enrolled Gilead Sciences
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This is a Phase 2 Randomized, Double-Blind, Placebo-Controlled Study of GS-5885, GS-9451, Tegobuvir and Ribavirin; GS-5885, GS-9451 and Tegobuvir; GS-5885, GS-9451 and Ribavirin in Interferon Ineligible or Intolerant Subjects with Chronic Genotype 1a or 1b HCV Infection.

Timeline

Start
2011-09
Primary completion
2013-01
Completion
2013-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ledipasvir Small molecule 90 mg
Comparator Ribavirin Small molecule 1000 mg
Comparator Ribavirin Small molecule 1200 mg
Comparator Tegobuvir Small molecule 30 mg
Comparator vedroprevir Small molecule 200 mg