Drugs / Prednicarbate
Prednicarbate
also known as
LAS189961 · Dermatop · Dermatop e emollient · HOE 777 · NSC-760042 · PREDNICARBATE COMPONENT OF LAS-41003 · Prednicarbato · S 77 0777
Small molecule targets NR3C1 via activation
Regulatory milestones approvals, filings & regulatory actions · 2 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Label expansion | US (FDA) | DERMATOP E EMOLLIENT | — | 1996-05-03 | fda.gov ↗ |
| Approved | US (FDA) | DERMATOP | — | 1991-09-23 | fda.gov ↗ |
Trials 1
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase not applicable1 trial · 1 missed | ||||||
| — | NCT00148746 | May 2004 → Sep 2006 | atopic eczema | Technical University Dresden | Completed | Missed primary |
| Comparator or background therapy4 trials | ||||||
| Phase 1 | NCT03399526 Comparator | Feb → May 2013 | psoriasis | Bayer | Completed | No outcome recorded |
| Phase 2 | NCT01096472 Comparator | Feb → Jun 2010 | tinea pedis | Almirall, S.A. | Completed | No outcome recorded |
| Phase 2 | NCT01102387 Comparator | Feb 2010 → Jul 2011 | candidiasis | Almirall, S.A. | Completed | No outcome recorded |
| Phase 2 | NCT01020994 Comparator | Nov 2009 → Jun 2010 | dermatitis | Almirall, S.A. | Completed | No outcome recorded |
Evidence & citations 13 cited values
Every value below carries the sentence it was read from. 6 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Prednicarbate | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03399526 ↗ |
| Known as | Dermatop | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00148746 ↗ |
| Known as | Dermatop e emollient | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200386 ↗ |
| Known as | HOE 777 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200386 ↗ |
| Known as | LAS189961 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01096472 ↗ |
| Known as | NSC-760042 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200386 ↗ |
| Known as | PREDNICARBATE COMPONENT OF LAS-41003 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200386 ↗ |
| Known as | Prednicarbato | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200386 ↗ |
| Known as | S 77 0777 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200386 ↗ |
| Action | Activate | “Glucocorticoid receptor agonist” CHEMBL1200386 ↗ |
| Modality | Small molecule | — CHEMBL1200386 ↗ |
| Route | Topical | “Once daily, topically” NCT01020994 ↗ |
| Target | NR3C1 | “Glucocorticoid receptor agonist” CHEMBL1200386 ↗ |