Drugs / Natamycin
Natamycin
also known as
Natacyn · ANTIBIOTIC A-5283 · CL 12,625 · Delvocid · E-235 · INS NO.235 · INS-235 · Mycophyt · +9 more
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | NATACYN | — | 1978-10-30 | fda.gov ↗ |
Trials 2
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 31 trial · 1 missed | ||||||
| Phase 3 | NCT02570321 | Nov 2015 → Jun 2018 | mycotic corneal ulcer | University of California, San Francisco | Completed | Missed primary |
| Phase 41 trial | ||||||
| Phase 4 | NCT07856680 | Oct 2026 → Mar 2027 expected | blepharitis | Brent Kramer | Not yet recruiting | No outcome recorded |
| Comparator or background therapy9 trials | ||||||
| Phase 1/2 | NCT00557362 Comparator | Nov 2007 → Aug 2008 | fungal keratitis | University of California, San Francisco | Completed | No outcome recorded |
| Phase 2 | NCT06463678 Comparator | Aug 2026 → Dec 2027 expected | fungal keratitis | IVIEW Therapeutics Inc. | Not yet recruiting | No outcome recorded |
| Phase 2/3 | NCT03230058 Background | Jan 2017 → Mar 2018 | fungal infectious disease | L.V. Prasad Eye Institute | Unknown | Missed primary |
| Phase 3 | NCT06411314 Comparator | Dec 2022 → Jul 2023 | vulvovaginal candidiasis | Avva Rus, JSC | Completed | No outcome recorded |
| Phase 3 | NCT05110001 Background | Aug 2022 → Dec 2024 | Acanthamoeba keratitis, fungal keratitis | University of California, San Francisco | Completed | Missed primary |
| Phase 3 | NCT02731638 Background | Sep 2016 → Jul 2018 | corneal ulcer, fungal keratitis | University of California, San Francisco | Completed | Missed primary |
| Phase 3 | NCT00996736 Comparator | Apr 2010 → Jul 2012 | corneal ulcer, fungal keratitis | University of California, San Francisco | Completed | Met primary |
| Phase 3 | NCT00516399 Comparator | Mar 2008 → Sep 2010 | fungal keratitis | University of California, Los Angeles | Terminated | No outcome recorded |
| — | NCT02328053 Background | Feb 2014 → Jul 2015 | mycotic corneal ulcer | Aravind Eye Care System | Unknown | No outcome recorded |
Press releases naming this drug 1 release
| Date | Issuer | Release |
|---|---|---|
| 2023-10-24 | Harrow Inc | Harrow Completes Transfer of NDAs and Launches FLAREX®, NATACYN®, TOBRADEX® ST, VERKAZIA®, and ZERVIATE® in the U.S. harrow.com ↗ |
Evidence & citations 20 cited values
Every value below carries the sentence it was read from. 12 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Natamycin | “Natamycin 5% ophthalmic suspension (Natacyn®) is FDA-approved for the treatment of fungal blepharitis, conjunctivitis, and keratitis caused by susceptible organisms (NATACYN US...” NCT07856680 ↗9“topical antifungal medications like natamycin eye drops and voriconazole eye drops” NCT02328053 ↗ “topical natamycin 5% alone” PMID 35044972 ↗ Jan 2022 |
| Known as | ANTIBIOTIC A-5283 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200656 ↗ |
| Known as | CL 12,625 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200656 ↗ |
| Known as | Delvocid | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200656 ↗ |
| Known as | E-235 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200656 ↗ |
| Known as | INS NO.235 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200656 ↗ |
| Known as | INS-235 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200656 ↗ |
| Known as | Mycophyt | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200656 ↗ |
| Known as | Myprozine | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200656 ↗ |
| Known as | Natacyn | “Natamycin 5% ophthalmic suspension (Natacyn®) is FDA-approved for the treatment of fungal blepharitis, conjunctivitis, and keratitis caused by susceptible organisms (NATACYN US...” NCT07856680 ↗ |
| Known as | Natamicina | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200656 ↗ |
| Known as | Natamycine | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200656 ↗ |
| Known as | NSC-759167 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200656 ↗ |
| Known as | Pimafucin | “Pimafucin® (natamycin) 100 mg vaginal suppositories” NCT06411314 ↗ |
| Known as | Pimaracin | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200656 ↗ |
| Known as | Pimaricin | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200656 ↗ |
| Known as | Synogil | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200656 ↗ |
| Known as | Tennecetin | ChEMBL registry synonym — accepted as the source's own label CHEMBL1200656 ↗ |
| Modality | Small molecule | — CHEMBL1200656 ↗ |
| Route | Topical | “Topical natamycin” NCT00557362 ↗ |