Drugs / Amonafide
Amonafide
also known as
Amonafida · AMONAFIDE CITRATE · Amonafide L-malate · Amonafide malate · AS1413 · Nafidimide · NSC-308847 · XAN 02 · +1 more
Trials 5 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT00087854 | Mar 2004 → Dec 2005 | prostate cancer | Xanthus Pharmaceuticals, Inc. | Completed | No outcome recorded |
| Phase 23 trials | ||||||
| Phase 2 | NCT01066494 | Jan → Sep 2010 | acute myeloid leukemia | Antisoma Research | Unknown | No outcome recorded |
| Phase 2 | NCT00273884 | Aug 2005 → Apr 2009 | acute myeloid leukemia | Xanthus Pharmaceuticals, Inc. | Completed | No outcome recorded |
| Phase 2 | NCT00074100 | Aug 2003 → Sep 2004 | breast cancer | Memorial Sloan Kettering Cancer Center | Completed | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT00715637 | Jun 2007 → Jun 2010 | acute myeloid leukemia | Antisoma Research | Unknown | No outcome recorded |
Evidence & citations 13 cited values
Every value below carries the sentence it was read from. 6 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | amonafide | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00074100 ↗ |
| Known as | Amonafida | ChEMBL registry synonym — accepted as the source's own label CHEMBL428676 ↗ |
| Known as | AMONAFIDE CITRATE | ChEMBL registry synonym — accepted as the source's own label CHEMBL428676 ↗ |
| Known as | Amonafide L-malate | “Amonafide L-malate (drug)” NCT00087854 ↗ |
| Known as | Amonafide malate | ChEMBL registry synonym — accepted as the source's own label CHEMBL428676 ↗ |
| Known as | AS1413 | “Phase III Randomized Study of Amonafide (AS1413) and Cytarabine Versus Daunorubicin and Cytarabine in Patients With Secondary Acute Myeloid Leukemia (AML)- the ACCEDE Study” NCT00715637 ↗ |
| Known as | Nafidimide | ChEMBL registry synonym — accepted as the source's own label CHEMBL428676 ↗ |
| Known as | NSC-308847 | ChEMBL registry synonym — accepted as the source's own label CHEMBL428676 ↗ |
| Known as | XAN 02 | ChEMBL registry synonym — accepted as the source's own label CHEMBL428676 ↗ |
| Known as | Xanafide | ChEMBL registry synonym — accepted as the source's own label CHEMBL428676 ↗ |
| Action | Inhibit | “Amonafide is a DNA intercalating agent and inhibitor of topoisomerase II” NCT00273884 ↗ |
| Modality | Small molecule | — CHEMBL428676 ↗ |
| Route | Intravenous | “amonafide IV over 1 hour” NCT00074100 ↗ |