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drugset / Trial / NCT01066494

A Pharmacokinetic and Efficacy Study of Amonafide L-malate (AS1413) in Combination With Cytarabine in Patients With Acute Myeloid Leukemia (AML)

NCT01066494 ↗

Phase 2 Unknown 20 enrolled Antisoma Research
Non-randomizedSingle-groupOpen-labelTreatment

Summary

A phase IIa study to evaluate the pharmacokinetic and efficacy of amonafide L-malate (AS1413) in combination with cytarabine in treating patients with acute myeloid leukemia (AML)

Timeline

Start
2010-01
Primary completion
2010-09
Completion
2011-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Amonafide Small molecule 600 mg/m2 Intravenous
Background Cytarabine Small molecule 200 mg/m2 Intravenous

Indications

acute myeloid leukemia