Drugs / PEGLOXENATIDE

Trials 11 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 17 trials
Phase 1 NCT02461914 Aug → Dec 2015 Jiangsu Hansoh Pharmaceutical Co., Ltd. Completed No outcome recorded
Phase 1 NCT02472236 Jun → Sep 2015 Jiangsu Hansoh Pharmaceutical Co., Ltd. Completed No outcome recorded
Phase 1 NCT02451527 May → Sep 2015 First Affiliated Hospital Xi'an Jiaotong University Completed No outcome recorded
Phase 1 NCT02447601 Mar → May 2015 type 2 diabetes mellitus Jiangsu Hansoh Pharmaceutical Co., Ltd. Completed No outcome recorded
Phase 1 NCT02467790 Feb 2015 → Mar 2016 type 2 diabetes mellitus Jiangsu Hansoh Pharmaceutical Co., Ltd. Unknown No outcome recorded
Phase 1 NCT01965496 Mar 2012 → Mar 2013 type 2 diabetes mellitus Jiangsu HengRui Medicine Co., Ltd. Completed No outcome recorded
Phase 1 NCT01976858 Jun → Sep 2011 type 2 diabetes mellitus Jiangsu HengRui Medicine Co., Ltd. Completed No outcome recorded
Phase 21 trial
Phase 2 NCT01965509 May 2012 → Aug 2013 type 2 diabetes mellitus Jiangsu HengRui Medicine Co., Ltd. Completed No outcome recorded
Phase 32 trials
Phase 3 NCT02477865 Mar 2014 → May 2016 type 2 diabetes mellitus Jiangsu Hansoh Pharmaceutical Co., Ltd. Unknown No outcome recorded
Phase 3 NCT02477969 Feb 2014 → Jun 2016 type 2 diabetes mellitus Jiangsu Hansoh Pharmaceutical Co., Ltd. Unknown No outcome recorded
Phase 41 trial
Phase 4 NCT07558863 Apr 2026 → Mar 2028 expected diabetic autonomic neuropathy, type 2 diabetes mellitus The First Affiliated Hospital with Nanjing Medical University Recruiting No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 12 sources stand behind the page.

FieldValueCited text
Known as PEGLOXENATIDE ChEMBL registry synonym — accepted as the source's own label CHEMBL4802213
Known as Peg-40 kd-loxenatide ChEMBL registry synonym — accepted as the source's own label CHEMBL4802213
Known as PEGylated Loxenatide “Evaluating PEGylated Loxenatide Injection(PEX168)in Monotherapy of Type 2 Diabetes Mellitus” NCT02477865
Known as PEX168 “Polyethylene glycol loxenatide (PEX168) is a novel long-acting glucagon-like peptide-1 receptor agonist for T2DM.” PMID 31396983 Dec 2019
9

NCT02477969

NCT01965496

NCT02461914

NCT02447601

NCT02472236

NCT02477865

NCT01965509

NCT01976858

NCT02451527

Known as Polyethylene Glycol Loxenatide Polyethylene Glycol Loxenatide (PEX168) is a new human glucagon-like peptide 1 (GLP-1) analogue that created on the basis of the Exenatide and modified by polyethylene glycol (PEG).” NCT01976858
3

“Two specific GLP-1RAs are used in this study: semaglutide at 0.5 mg once weekly, or polyethylene glycol loxenatide at 0.2 mg once weekly.” NCT07558863

Polyethylene glycol loxenatide (PEX168) is a novel long-acting glucagon-like peptide-1 receptor agonist for T2DM.” PMID 31396983 Dec 2019

Polyethylene Glycol Loxenatide (PEX168) is a new human glucagon-like peptide 1 (GLP-1) analogue” NCT01965509

Modality Peptide “a new human glucagon-like peptide 1 (GLP-1) analogue” NCT01965496
Route Subcutaneous “A injection administered subcutaneously” NCT01965496