drugset / Trial / NCT01976858

A Phase I Study of 8-week Continuous Treatment With Polyethylene Glycol Loxenatide in Patients With Type 2 Diabetes

NCT01976858

RandomizedParallel-groupQuadruple-blindTreatment

Summary

Polyethylene Glycol Loxenatide (PEX168) is a new human glucagon-like peptide 1 (GLP-1) analogue that created on the basis of the Exenatide and modified by polyethylene glycol (PEG). This study aims to evaluate the PK, PD and safety by 8-week continuous treatment of PEX168.

Timeline

Start
2011-06
Primary completion
2011-09
Completion
2011-12

Drugs

EvaluationDrugModalityDoseRoute
Subject PEGLOXENATIDE Peptide 50 ug Subcutaneous
Subject PEGLOXENATIDE Peptide 100 ug Subcutaneous
Subject PEGLOXENATIDE Peptide 200 ug Subcutaneous
Subject PEGLOXENATIDE Peptide 300 ug Subcutaneous