drugset / Trial / NCT01976858
A Phase I Study of 8-week Continuous Treatment With Polyethylene Glycol Loxenatide in Patients With Type 2 Diabetes
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Polyethylene Glycol Loxenatide (PEX168) is a new human glucagon-like peptide 1 (GLP-1) analogue that created on the basis of the Exenatide and modified by polyethylene glycol (PEG). This study aims to evaluate the PK, PD and safety by 8-week continuous treatment of PEX168.
Timeline
- Start
- 2011-06
- Primary completion
- 2011-09
- Completion
- 2011-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | PEGLOXENATIDE | Peptide | 50 ug | Subcutaneous |
| Subject | PEGLOXENATIDE | Peptide | 100 ug | Subcutaneous |
| Subject | PEGLOXENATIDE | Peptide | 200 ug | Subcutaneous |
| Subject | PEGLOXENATIDE | Peptide | 300 ug | Subcutaneous |