Recombinant Follicle Stimulating Hormone
Trials 1
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 41 trial | ||||||
| Phase 4 | NCT02625519 | Dec 2015 → Jan 2019 | — | Instituto Bernabeu | Unknown | No outcome recorded |
| Comparator or background therapy9 trials | ||||||
| Phase 3 | NCT00669786 Comparator | — | — | Instituto Valenciano de Infertilidad, IVI VALENCIA | Completed | No outcome recorded |
| Phase 4 | NCT04992468 Background | Oct 2021 → Apr 2023 | infertility disorder | Fundacion Dexeus | Completed | No outcome recorded |
| Phase 4 | NCT03252223 Comparator | Oct 2017 → Jun 2021 | anovulation, polycystic ovary syndrome | University of California, San Diego | Completed | No outcome recorded |
| Phase 4 | NCT03118830 Comparator | Apr → Nov 2017 | — | Cairo University | Completed | No outcome recorded |
| Phase 4 | NCT01760278 Background | Dec 2012 → Mar 2013 | aneuploidy, low implantation of placenta, pregnancy disorder with abortive outcome | Bloom IVF and Fertility Centre | Unknown | No outcome recorded |
| Phase 4 | NCT00553293 Comparator | Aug 2003 → Nov 2004 | infertility disorder | Rigshospitalet, Denmark | Completed | No outcome recorded |
| — | NCT05670795 Background | Jan 2023 → May 2024 | infertility disorder | Bezmialem Vakif University | Unknown | No outcome recorded |
| — | NCT05567731 Background | Oct 2022 → Dec 2023 | infertility disorder | Tanta University | Completed | No outcome recorded |
| — | NCT01634724 Background | Jul 2012 | — | Nanjing University | Unknown | No outcome recorded |
Press releases naming this drug 2 releases
| Date | Issuer | Release |
|---|---|---|
| 2021-06-29 | Ferring Pharmaceuticals | Ferring presents new data at ESHRE 2021 supporting the use of Rekovelle® (follitropin delta) for individualized fertility treatment ferring.com ↗ |
| 2001-05-16 | Alkermes, Inc. | Alkermes and Serono to Proceed With Development of Long-acting Formulation of Recombinant Human Follicle Stimulating Hormone (R-hFSH) alkermes.com ↗ |
Evidence & citations 11 cited values
Every value below carries the sentence it was read from. 12 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Recombinant Follicle Stimulating Hormone | “Two weeks later, if E2 in serum was ≤40 pg/ml and absence of follicular activity was detected, the stimulation of ovaries was started by recombinant follicle-stimulating...” NCT01634724 ↗9“recombinant follicle stimulating hormone (rFSH) 225-300 IU (Gonal-F®/Puregon®/ Ovaleap®/Rekovelle®)” NCT04992468 ↗ “recombinant Follicle-Stimulating Hormone for controlled ovarian hyperstimulation (COH)” NCT05567731 ↗ |
| Known as | follicle stimulating hormone | “follicle stimulating hormone (FSH) administered subcutaneously” NCT03252223 ↗ |
| Known as | Gonal-F | “Two weeks later, if E2 in serum was ≤40 pg/ml and absence of follicular activity was detected, the stimulation of ovaries was started by recombinant follicle-stimulating...” NCT01634724 ↗2“recombinant follicle stimulating hormone (rFSH) 225-300 IU (Gonal-F®/Puregon®/ Ovaleap®/Rekovelle®)” NCT04992468 ↗ “with either HMG(Menogon; Ferring, Switzerland) or rFSH (Gonal-f; Merck Serono, Germany)” NCT05567731 ↗ |
| Known as | Ovaleap | “recombinant follicle stimulating hormone (rFSH) 225-300 IU (Gonal-F®/Puregon®/ Ovaleap®/Rekovelle®)” NCT04992468 ↗ |
| Known as | Puregon | “recombinant follicle stimulating hormone (rFSH) 225-300 IU (Gonal-F®/Puregon®/ Ovaleap®/Rekovelle®)” NCT04992468 ↗ |
| Known as | r-FSH | “Highly purified hMG (hp-hMG) has recently shown better cycle outcome than the recombinant FSH (rFSH)” PMID 18583332 ↗ Jun 20085“recombinant follicle stimulating hormone (rFSH) 225-300 IU (Gonal-F®/Puregon®/ Ovaleap®/Rekovelle®)” NCT04992468 ↗ “Human Menopausal Gonadotropin (HMG) & - Recombinant Follicle Stimulating Hormone (r-FSH)” NCT00669786 ↗ “with either HMG(Menogon; Ferring, Switzerland) or rFSH (Gonal-f; Merck Serono, Germany)” NCT05567731 ↗ “using recombinant FSH (r-FSH), injected sc for 3 days at any one dose” NCT03252223 ↗ “recombinant Follicle Stimulating Hormone (rFSH)” NCT01760278 ↗ |
| Known as | recFSH | “Two weeks later, if E2 in serum was ≤40 pg/ml and absence of follicular activity was detected, the stimulation of ovaries was started by recombinant follicle-stimulating...” NCT01634724 ↗ |
| Known as | recombinant FSH | “using recombinant FSH (r-FSH), injected sc for 3 days at any one dose” NCT03252223 ↗ |
| Known as | Rekovelle | “recombinant follicle stimulating hormone (rFSH) 225-300 IU (Gonal-F®/Puregon®/ Ovaleap®/Rekovelle®)” NCT04992468 ↗ |
| Modality | Protein / enzyme biologic | “recombinant FSH (rFSH)” PMID 18024487 ↗ Nov 2007 |
| Route | Subcutaneous | “recombinant Follicle Stimulating Hormone (rFSH) by S.C. injection” NCT01760278 ↗ |