Drugs / loberamisal
last change Dec 2025 re-read 3 minutes ago

loberamisal

Small molecule

Developed for
ischemic stroke
Investigated by
Beijing Tiantan Hospital · Neurodawn Pharmaceutical Co., Ltd.

Trials 2

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial · 1 missed
Phase 2 NCT06429384 Jun → Nov 2023 ischemic stroke Beijing Tiantan Hospital Completed Missed primary
Phase 31 trial
Phase 3 NCT06517173 Jul 2024 → Apr 2025 ischemic stroke Beijing Tiantan Hospital Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as loberamisal “Loberamisal, a novel agent that dissociates the post-synaptic density protein 95/neuronal nitric oxide synthase complex and potentiates the α2-containing γ-aminobutyric acid...” PMID 41344725 ↗ Dec 2025
1

“Loberamisal is a small-molecule agent that inhibits the nNOS-postsynaptic density protein 95 coupling and enhances α2-containing γ-aminobutyric acid type A receptor, which has...” PMID 41218852 ↗ Nov 2025

Action Inhibit “inhibits the nNOS-postsynaptic density protein 95 coupling” PMID 41218852 ↗ Nov 2025
Modality Small molecule “Loberamisal is a small-molecule agent” PMID 41218852 ↗ Nov 2025
Route Intravenous “intravenous loberamisal” PMID 41344725 ↗ Dec 2025