Drugs / E3810
last change Jun 2025 re-read 3 minutes ago

E3810

also known as Pariet · Rabeprazole · Rabeprazole Sodium
Developed for
active peptic ulcer disease · gastroesophageal reflux disease · peptic esophagitis
Investigated by
Eisai Inc.

Trials 4

20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT01153659 Jul → Aug 2010 — Eisai Inc. Completed No outcome recorded
Phase 2/32 trials · 1 met primary
Phase 2/3 NCT01397448 Jul 2011 → Mar 2013 active peptic ulcer disease Eisai Inc. Completed Met primary
Phase 2/3 NCT00770913 Oct 2008 → Nov 2009 peptic esophagitis Eisai Inc. Completed No outcome recorded
Phase 31 trial
Phase 3 NCT00165646 Sep 2004 → Oct 2005 gastroesophageal reflux disease Eisai Inc. Completed No outcome recorded

Press releases naming this drug 18 releases

DateIssuerRelease
2025-06-02 Eisai Inc. Eisai to Launch “Pariet® S,” the First Proton Pump Inhibitor RX-to-OTC in Japan - Same Dosage of the Active Ingredient Rabeprazole Sodium as the Prescription Product - eisai.com ↗
2025-03-28 Eisai Inc. EISAI TO DIVEST RIGHTS FOR PARIET® IN CHINA TO PEAK PHARMA eisai.com ↗
2025-03-21 Eisai Inc. Proton Pump Inhibitor “Pariet® S” Approved in Japan as RX-to-OTC Switch Same Dosage of the Active Ingredient Rabeprazole Sodium as the Prescription Product eisai.com ↗
2017-09-22 Eisai Inc. Additional Dosage and Administration of Proton Pump Inhibitor Pariet® 5 mg Tablets, 10 mg Tablets Approved in Japan for Maintenance Therapy of Proton Pump Inhibitor Resistant Reflux Esophagitis eisai.com ↗
2016-10-28 Eisai Inc. Application Submitted for Proton Pump Inhibitor Pariet® in Japan Seeking Approval for Additional Dosage and Administration for Maintenance Therapy of Proton Pump Inhibitor Resistant Reflux Esophagitis eisai.com ↗
2015-02-24 Eisai Inc. EISAI LAUNCHES PROTON PUMP INHIBITOR PARIET® TABLETS 5 MG IN JAPAN eisai.com ↗
2014-12-26 Eisai Inc. EISAI RECEIVES APPROVAL FOR INDICATION EXPANSION OF PROTON PUMP INHIBITOR PARIET® FOR USE IN PREVENTION OF RECURRENT GASTRIC OR DUODENAL ULCER CAUSED BY LOW-DOSE ASPIRIN THERAPY AND ADDITIONAL 5 MG TABLET FORMULATION IN JAPAN eisai.com ↗
2014-02-13 Eisai Inc. EISAI ANNOUNCES LAUNCH OF PARIET® TRIPLE FORMULATION COMBINATION PACKS RABECURE® 400 AND 800 AND RABEFINE®, FOR PRIMARY AND SECONDARY H. PYLORI ERADICATION RESPECTIVELY, IN JAPAN eisai.com ↗
2013-11-28 Eisai Inc. EISAI SUBMITS APPLICATION FOR PROTON PUMP INHIBITOR PARIET® IN JAPAN SEEKING INDICATION EXPANSION FOR PREVENTION OF RECURRENT GASTRIC OR DUODENAL ULCER CAUSED BY LOW-DOSE ASPIRIN THERAPY AND APPROVAL OF NEW FORMULATION eisai.com ↗
2013-08-21 Eisai Inc. EISAI RECEIVES APPROVAL TO MARKET PARIET® TRIPLE FORMULATION PACKS RABECURE® 400 AND 800 AND RABEFINE®, FOR PRIMARY AND SECONDARY H. PYLORI ERADICATION RESPECTIVELY, IN JAPAN eisai.com ↗
2012-05-31 Eisai Inc. EISAI SEEKS APPROVAL TO MARKET PARIET® TRIPLE FORMULATION PACK IN JAPAN FOR HELICOBACTER PYLORI ERADICATION eisai.com ↗
2011-09-02 Eisai Inc. EISAI DISCONTINUES DEVELOPMENT OF PARIET®/ACIPHEX® EXTENDED-RELEASE CAPSULES, 50 MG eisai.com ↗

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as E3810 “Prevention of Recurrent Gastric or Duodenal Ulcers Caused by Low-dose Aspirin With Rabeprazole (E3810) Treatment (Planetarium Study)” NCT01397448 ↗
3

NCT00165646 ↗

NCT01153659 ↗

NCT00770913 ↗

Known as Pariet “To investigate the efficacy and safety of a 4-week treatment of 5 mg/day or 10 mg/day of E3810 (Pariet (Rabeprazole Sodium)) in patients with non-erosive gastroesophageal...” NCT00165646 ↗
Known as Rabeprazole “Prevention of Recurrent Gastric or Duodenal Ulcers Caused by Low-dose Aspirin With Rabeprazole (E3810) Treatment (Planetarium Study)” NCT01397448 ↗
Known as Rabeprazole Sodium “To investigate the efficacy and safety of a 4-week treatment of 5 mg/day or 10 mg/day of E3810 (Pariet (Rabeprazole Sodium)) in patients with non-erosive gastroesophageal...” NCT00165646 ↗
Route Oral “E3810 5mg: once daily orally for 4 weeks” NCT00165646 ↗