Drugs / Fibrin Sealant
Fibrin Sealant
Trials 10
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT00161759 | Mar 2002 → Jan 2004 | — | Baxter Healthcare Corporation | Completed | No outcome recorded |
| Phase 21 trial · 1 met primary | ||||||
| Phase 2 | NCT01244425 | Nov 2010 → Jul 2011 | — | Baxter Healthcare Corporation | Completed | Met primary |
| Phase 2/31 trial | ||||||
| Phase 2/3 | NCT04621799 | Jun 2018 → Dec 2020 | lumbar disk degenerative disorder, lumbar disk disease, radiculopathy | Pauza, Kevin, MD | Unknown | No outcome recorded |
| Phase 32 trials · 1 missed | ||||||
| Phase 3 | NCT00028951 | Jan 2003 → Dec 2005 | lymphedema, vulva cancer | Gynecologic Oncology Group | Completed | Missed primary |
| Phase 3 | NCT00161915 | Dec 2000 → Jan 2004 | esophageal varices | Baxter Healthcare Corporation | Completed | No outcome recorded |
| Phase 42 trials | ||||||
| Phase 4 | NCT07455591 | Jan → Aug 2024 | osteoarthritis, knee | Singapore General Hospital | Completed | No outcome recorded |
| Phase 4 | NCT01538927 | Apr → Dec 2012 | periodontitis | Chhattisgarh Dental College and Research Institute | Completed | No outcome recorded |
| Phase not applicable3 trials · 1 missed | ||||||
| — | NCT01649505 | Jan 2011 → Jan 2012 | breast cancer | OHSU Knight Cancer Institute | Terminated | No outcome recorded Stop: Enrollment |
| — | NCT00440921 | Dec 2008 → Dec 2009 | osteoarthritis, knee | Sanquin Research & Blood Bank Divisions | Withdrawn | No outcome recorded |
| — | NCT00506311 | Feb 2003 → Dec 2007 | melanoma | M.D. Anderson Cancer Center | Completed | Missed primary |
| Comparator or background therapy3 trials | ||||||
| Phase 2 | NCT02343263 Comparator | Mar 2015 → May 2017 | neuropathy, painful | Indiana University | Terminated | No outcome recorded |
| Phase 3 | NCT01126060 Comparator | Feb 2010 → Jan 2011 | thyroid gland carcinoma | Samsung Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT01472913 Comparator | Aug 2010 → Aug 2013 | — | Hvidovre University Hospital | Completed | No outcome recorded |
Evidence & citations 5 cited values
Every value below carries the sentence it was read from. 14 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Fibrin sealant | ClinicalTrials.gov intervention name — accepted as the source's own label NCT04621799 ↗ |
| Known as | TISSEEL VH | “A Phase III Clinical Trial Use of TISSEEL VH Fibrin Sealant to Reduce Lymphedema Incidence After Inguinal Lymph Node Dissection Performed in the Management of Vulvar Malignancies” NCT00028951 ↗ |
| Known as | VeraSeal | “This study is conducted as a pilot trial to assess the added benefit of the VeraSeal fibrin sealant to TXA on postoperative outcomes following TKR.” NCT07455591 ↗ |
| Modality | Protein / enzyme biologic | “fibrin sealant, which is derived from the proteins that help form blood clots in blood” NCT02343263 ↗ |
| Route | Other | “VH fibrin sealant sprayed into the groin followed by sutured closure (FS).” PMID 18482765 ↗ May 2008 |