drugset / Trial / NCT01126060

Efficacy of Fibrin Sealant to Reduce the Amount of Post-thyroidectomy Drain

NCT01126060

Phase 3 Completed 78 enrolled Samsung Medical Center
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Fibrin sealant has been studied to reduce post-thyroidectomy drain and hospital stay as well. However, no strong evidence from well-designed clinical trials is available. Harmonic scalpel is a ultrasonic vibrating scissors which makes it easy to cut and coagulate the tissues, thus reducing op time and postoperative drain, which is important to minimize hospital stay. The investigators hypothesized that fibrin sealant combined with harmonic scalpel-assisted procedure could guarantee no-drain postoperative care in total thyroidectomy with anterior compartment neck dissection.

Timeline

Start
2010-02
Primary completion
2011-01
Completion
2011-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Fibrinogen Concentrate Human Protein / enzyme biologic 1 unknown