Drugs / KT502
last change Jul 2026 re-read 3 minutes ago

KT502

Monoclonal antibody targets CD19 via depletion

Developed for
rheumatoid arthritis
Investigated by
Kali Therapeutics, Inc.

Trials 1

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT07564154 Jul 2026 → Dec 2027 expected rheumatoid arthritis Kali Therapeutics, Inc. Not yet recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2026-05-18 Kali Therapeutics, Inc. Results Kali Therapeutics Announces Oral Presentation of KT502, a Novel CD19 x CD3 T-Cell Engager, at the EULAR 2026 Annual Congress kalitherapeutics.com ↗
In our NHP studies, the molecule proved to be very potent in depleting B-cells, yet it induced only low and transitory cytokine releases.

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as KT502 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07564154 ↗
Action Deplete “KT502 is a monoclonal antibody that depletes B cells by targeting CD19 and CD3” NCT07564154 ↗
Modality Monoclonal antibody “KT502 is a monoclonal antibody that depletes B cells by targeting CD19 and CD3” NCT07564154 ↗
Route Subcutaneous “KT502 administered subcutaneously” NCT07564154 ↗
Target CD19 “KT502 is a monoclonal antibody that depletes B cells by targeting CD19 and CD3” NCT07564154 ↗