drugset / Trial / NCT07564154

A First-in-human Study of KT502 Administered Subcutaneously to Adult Participants With Rheumatoid Arthritis (RA)

NCT07564154 ↗

Phase 1 Not yet recruiting 27 enrolled Kali Therapeutics, Inc.
Non-randomizedSequentialOpen-labelTreatment

Summary

This is a Phase 1, open-label, first-in-human study to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of KT502 administered subcutaneously to participants with Rheumatoid Arthritis (RA). The study will have 2 parts: Part A is a single ascending dose finding (SAD) and Part B is dose escalation by fractionated dosing.

Timeline

Start
2026-07
Primary completion
2027-12
Completion
2028-07

Drugs

EvaluationDrugModalityDoseRoute
Subject KT502 Monoclonal antibody — Subcutaneous

Indications