Drugs / Phenoxybenzamine
Phenoxybenzamine
also known as
Bensylyt · Benzylyt · Dibenylin · Dibenyline · Dibenzylin · Dibenzyline · Dibenzyline chloride · Dibenzyline hydrochloride · +6 more
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | DIBENZYLINE | — | 1953-01-26 | fda.gov ↗ |
Trials 3 · a red edge is where a trial was stopped
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| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 22 trials | ||||||
| Phase 2 | NCT00770705 | Oct 2008 → Aug 2010 | congenital heart disease | Vanderbilt University | Withdrawn | No outcome recorded |
| Phase 2 | NCT00569855 | Feb 2001 → Aug 2010 | — | University of Arkansas | Completed | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT00620945 | Jun 2006 → Feb 2009 | congenital anomaly of cardiovascular system | The Cleveland Clinic | Terminated | No outcome recorded |
Also used as a comparator or background therapy in 3 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 31 trial | ||||||
| Phase 3 | NCT03176693 Comparator | May 2017 → Jan 2020 | paraganglioma, pheochromocytoma | University of California, Los Angeles | Completed | No outcome recorded |
| Phase 42 trials | ||||||
| Phase 4 | NCT05702944 Comparator | Jan 2023 → Aug 2027 expected | paraganglioma, pheochromocytoma | Seoul National University Hospital | Recruiting | No outcome recorded |
| Phase 4 | NCT01379898 Comparator | Dec 2011 → Jan 2018 | pheochromocytoma | University Medical Center Groningen | Completed | No outcome recorded |
Evidence & citations 18 cited values
Every value below carries the sentence it was read from. 7 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Phenoxybenzamine | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00620945 ↗ |
| Known as | Bensylyt | ChEMBL registry synonym — accepted as the source's own label CHEMBL753 ↗ |
| Known as | Benzylyt | ChEMBL registry synonym — accepted as the source's own label CHEMBL753 ↗ |
| Known as | Dibenylin | ChEMBL registry synonym — accepted as the source's own label CHEMBL753 ↗ |
| Known as | Dibenyline | ChEMBL registry synonym — accepted as the source's own label CHEMBL753 ↗ |
| Known as | Dibenzylin | ChEMBL registry synonym — accepted as the source's own label CHEMBL753 ↗ |
| Known as | Dibenzyline | “Phenoxybenzamine (Dibenzyline: Wellspring Pharmaceutical Corporation, Bradenton, FL) is a haloalkylamine that irreversibly blocks both α-1 and α-2 adrenergic receptors.” NCT00770705 ↗ |
| Known as | Dibenzyline chloride | ChEMBL registry synonym — accepted as the source's own label CHEMBL753 ↗ |
| Known as | Dibenzyline hydrochloride | ChEMBL registry synonym — accepted as the source's own label CHEMBL753 ↗ |
| Known as | Dibenzyran | ChEMBL registry synonym — accepted as the source's own label CHEMBL753 ↗ |
| Known as | Fenoxibenzamina | ChEMBL registry synonym — accepted as the source's own label CHEMBL753 ↗ |
| Known as | NSC-37448 | ChEMBL registry synonym — accepted as the source's own label CHEMBL753 ↗ |
| Known as | Phenoxybenzamine chloride | ChEMBL registry synonym — accepted as the source's own label CHEMBL753 ↗ |
| Known as | Phenoxybenzamine hcl | ChEMBL registry synonym — accepted as the source's own label CHEMBL753 ↗ |
| Known as | PHENOXYBENZAMINE HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL753 ↗ |
| Action | Inhibit | “acts by irreversibly blocking the alpha adrenergic receptors” NCT00620945 ↗ |
| Modality | Small molecule | “Phenoxybenzamine (Dibenzyline: Wellspring Pharmaceutical Corporation, Bradenton, FL) is a haloalkylamine” NCT00770705 ↗ |
| Route | Intravenous | “given i.v.” NCT00569855 ↗ |