Drugs / PHOX2B PC-CAR T Cells
last change Jun 2025 re-read 3 minutes ago

PHOX2B PC-CAR T Cells

Cell therapy targets PHOX2B

Developed for
neuroblastoma
Investigated by
Alliance for Cancer Gene Therapy · Children's Cancer Research Fund · Children's Hospital of Philadelphia · Stephan Grupp MD PhD

Trials 1

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT07007117 Jun 2025 → Jun 2032 expected neuroblastoma Stephan Grupp MD PhD Active not recruiting No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as PHOX2B PC-CAR T cells “administering PHOX2B PC-CAR T cells in patients with advanced, high-risk neuroblastoma” NCT07007117 ↗
1

NCT07007117 ↗

Modality Cell therapy “autologous human T cells that have been genetically modified” NCT07007117 ↗
Target PHOX2B “PHOX2B-targeting chimeric antigen receptor (CAR) transgene” NCT07007117 ↗