drugset / Trial / NCT07007117
PHOX2B PC-CAR T Cells for Relapsed Neuroblastoma
Phase 1
Active not recruiting
38 enrolled
Stephan Grupp MD PhD
Alliance for Cancer Gene Therapy · collabChildren's Cancer Research Fund · collabChildren's Hospital of Philadelphia · collab
Non-randomizedSequentialOpen-labelTreatment
Summary
This is a first in human dose escalation trial to determine the safety of administering PHOX2B PC-CAR T cells in patients with advanced, high-risk neuroblastoma.
Timeline
- Start
- 2025-06-20
- Primary completion
- 2032-06-30
- Completion
- 2035-06-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | PHOX2B PC-CAR T Cells | Cell therapy | — | — |