Drugs / Lactobacillus brevis CD2

Trials 8

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 22 trials
Phase 2 NCT05175833 Sep 2020 → Jan 2021 COVID-19, bacterial pneumonia Universidade de Passo Fundo Completed No outcome recorded
Phase 2 NCT04398511 Jan → Nov 2019 malposition of teeth with or without hypodontia/oligodontia, mucositis, primary bacterial infectious disease Universidade de Passo Fundo Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT02085694 Mar → Nov 2014 chemotherapy-induced oral mucositis Catholic University of the Sacred Heart Unknown No outcome recorded
Phase 35 trials
Phase 3 NCT02390687 Apr 2015 → Sep 2016 chronic periodontitis Next Gen Pharma India Pvt. Ltd. Completed No outcome recorded
Phase 3 NCT02357771 Apr → Aug 2015 malposition of teeth with or without hypodontia/oligodontia Next Gen Pharma India Pvt. Ltd. Completed No outcome recorded
Phase 3 NCT02329353 Feb 2015 → Nov 2016 chronic periodontitis Next Gen Pharma India Pvt. Ltd. Completed No outcome recorded
Phase 3 NCT02203812 Jan 2015 → Feb 2016 chronic periodontitis CD Pharma India Pvt. Ltd. Completed No outcome recorded
Phase 3 NCT02121665 Jul 2014 → Jan 2016 chronic periodontitis CD Pharma India Pvt. Ltd. Completed No outcome recorded
Comparator or background therapy1 trial
Phase 3 NCT01797952 Comparator Nov 2015 → Oct 2016 chemotherapy-induced oral mucositis All India Institute of Medical Sciences Withdrawn No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 10 sources stand behind the page.

FieldValueCited text
Known as Lactobacillus brevis CD2 “oral gel containing Streptococcus salivarius K12 (2 billion live bacilli) and Lactobacillus brevis CD2 (4 billion live bacilli)” NCT05175833 ↗
8

“Lactobacillus brevis CD2 lozenges reduce radiation- and chemotherapy-induced mucositis in patients with head and neck cancer” PMID 21741230 ↗ Jul 2011

“Each Lactobacillus brevis CD2 lozenge contains not less than 1 billion Colony Forming Unit of L. brevis CD2” NCT02357771 ↗

“Each probiotic lozenge contains not less than 1 billion colony forming unit of Lactobacillus brevis CD2” NCT02390687 ↗

“Each lozenge contains at least 1 billion colony forming units of Lactobacillus brevis CD2.” NCT02203812 ↗

“Each Inersan lozenge contains not less than 1 billion CFU of Lactobacillus brevis CD2” NCT02121665 ↗

“Lactobacillus brevis CD2 in lozenges containing 4 billion CFU.” NCT04398511 ↗

NCT02085694 ↗

NCT02329353 ↗

Known as L brevis “probiotic Lactobacillus brevis CD2 (L brevis) is benefic in this condition.” NCT04398511 ↗
Known as L. brevis CD2 “Each Lactobacillus brevis CD2 lozenge contains not less than 1 billion Colony Forming Unit of L. brevis CD2” NCT02357771 ↗
2

“daily treatment with lozenges containing either L. brevis CD2 or placebo” PMID 21741230 ↗ Jul 2011

“L. brevis CD2 Lozenges” NCT02203812 ↗

Known as Lactobacillus CD 2 “Recently investigators have shown effectiveness of a probiotic Lactobacillus CD 2 in reducing incidence and severity of chemo-radiotherapy induced mucositis in head and neck...” NCT01797952 ↗
Modality Other / unclassified “It contains not less than 2x109 (2 billion) viable cells of Lactobacillus CD2 as active ingredient.” NCT01797952 ↗
Route Oral “one lozenge to be taken every 2-3 hours preferably not before the meal” NCT01797952 ↗