drugset / Trial / NCT02085694

Lactobacillus Brevis CD2 Preventing Oral Mucositis

NCT02085694 ↗

Phase 2/3 Unknown 10 enrolled Catholic University of the Sacred Heart
NaSingle-groupOpen-labelPrevention

Summary

A pilot study on efficacy of Lactobacillus CD2 lozenges in preventing oral mucositis (OM) by high-dose chemotherapy with autologous hematopoietic stem cell transplantation. To test whether the probiotic Lactobacillus brevis CD2 lozenges can reduce the incidence and severity of high-dose chemotherapy conditioning regimen induced OM in patients undergoing HSCT. Clinical activity will be defined as reduction in the incidence of chemotherapy induced OM in the patients undergoing HSCT.

Timeline

Start
2014-03
Primary completion
2014-11
Completion
2014-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Lactobacillus brevis CD2 Other / unclassified — Oral