Drugs / fosdagrocorat
last change Apr 2019 re-read 2 minutes ago

fosdagrocorat

also known as PF-04171327

Small molecule targets NR3C1

Developed for
rheumatoid arthritis
Investigated by
Pfizer

Trials 6 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials
Phase 1 NCT01362673 May → Aug 2011 Pfizer Completed No outcome recorded
Phase 1 NCT01199900 Aug → Sep 2010 Pfizer Completed No outcome recorded
Phase 1 NCT00987038 Sep → Dec 2009 Pfizer Completed No outcome recorded
Phase 1 NCT00812825 Jan → Jul 2009 Pfizer Completed No outcome recorded
Phase 22 trials
Phase 2 NCT01393639 Sep 2011 → Jun 2014 rheumatoid arthritis Pfizer Completed No outcome recorded
Phase 2 NCT00938587 Oct 2009 → Jul 2010 rheumatoid arthritis Pfizer Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 9 sources stand behind the page.

FieldValueCited text
Known as fosdagrocorat “PF-04171327 (fosdagrocorat) is a phosphate ester prodrug of PF-00251802 (dagrocorat), a selective high-affinity partial agonist of the glucocorticoid receptor” PMID 29112329 Nov 2017
1

fosdagrocorat (PF-04171327), a dissociated agonist of the” PMID 31168411 Apr 2019

Known as PF-04171327 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01362673
5

NCT00938587

NCT00987038

NCT01199900

NCT00812825

NCT01393639

Modality Small molecule CHEMBL3137316
Route Oral “One 25 mg tablet administered once a day for 15 days” NCT00987038
Target NR3C1 “Glucocorticoid receptor modulator” CHEMBL3137316