Phase 1 16 trials
Phase 1
NCT07140016 Sep 2025 → Dec 2029 expected non-small cell lung carcinoma Astellas Pharma Global Development, Inc.
Recruiting
No outcome recorded
Phase 1
NCT06225427 Jul 2024 → May 2027 expected non-small cell lung carcinoma University of Michigan Rogel Cancer Center
Recruiting
No outcome recorded
Phase 1
NCT06222580 Feb 2024 → Jan 2027 expected acute myeloid leukemia with mutated NPM1 , acute myeloid leukemia, FLT3 internal tandem duplication , acute myeloid leukemia, MLL gene rearrangement Uma Borate
Recruiting
No outcome recorded
Phase 1
NCT05756777 Oct 2023 → Apr 2027 expected acute myeloid leukemia Memorial Sloan Kettering Cancer Center
Recruiting
No outcome recorded
Phase 1
NCT05330377 Mar 2023 → May 2027 acute myeloid leukemia Ayman H Qasrawi
Withdrawn
No outcome recorded
Phase 1
NCT05546580 Nov 2022 → Nov 2025 overdue acute myeloid leukemia Oryzon Genomics S.A.
Recruiting
No outcome recorded
Phase 1
NCT04655391 Jun 2022 → Dec 2023 acute myeloid leukemia City of Hope Medical Center
Withdrawn
No outcome recorded
Phase 1
NCT05024552 Feb 2022 → Feb 2027 expected acute myeloid leukemia, FLT3 internal tandem duplication H. Lee Moffitt Cancer Center and Research Institute
Recruiting
No outcome recorded
Phase 1
NCT05010772 Oct 2021 → Dec 2026 expected acute myeloid leukemia M.D. Anderson Cancer Center
Recruiting
No outcome recorded
Phase 1
NCT04699877 Jan 2021 → Jul 2022 impaired renal function disease , medulloadrenal hyperfunction Astellas Pharma Global Development, Inc.
Completed
No outcome recorded
Phase 1
NCT04336982 Aug 2020 → Oct 2023 acute myeloid leukemia Celgene Corporation
Terminated
No outcome recorded
Phase 1
NCT03625505 Oct 2018 → Aug 2021 acute myeloid leukemia AbbVie
Completed
No outcome recorded
Phase 1
NCT02456883 Mar 2016 → May 2017 cancer Astellas Pharma Global Development, Inc.
Completed
No outcome recorded
Phase 1
NCT02571816 Oct 2015 → Mar 2016 —
Astellas Pharma Global Development, Inc.
Completed
No outcome recorded
Phase 1
NCT02236013 Jan 2015 → Jul 2021 acute myeloid leukemia Astellas Pharma Global Development, Inc.
Completed
No outcome recorded
Phase 1
NCT02181660 Jun 2014 → Jun 2016 acute myeloid leukemia Astellas Pharma Inc
Completed
No outcome recorded
Show 6 more trials Phase 1/2 13 trials
Phase 1/2
NCT06561880 Oct 2024 → Sep 2026 expected acute myeloid leukemia Institute of Hematology & Blood Diseases Hospital, China
Recruiting
No outcome recorded
Phase 1/2
NCT06235801 May 2024 → Oct 2027 expected myeloid leukemia M.D. Anderson Cancer Center
Active not recruiting
No outcome recorded
Phase 1/2
NCT05520567 Jan 2023 → Jul 2028 expected acute myeloid leukemia Astellas Pharma Global Development, Inc.
Active not recruiting
No outcome recorded
Phase 1/2
NCT05028751 Aug 2022 → Apr 2024 acute myeloid leukemia Kronos Bio
Terminated
No outcome recorded
Phase 1/2
NCT05010122 Jul 2021 → Jan 2028 expected acute myeloid leukemia , myelodysplastic syndrome M.D. Anderson Cancer Center
Recruiting
No outcome recorded
Phase 1/2
NCT04240002 Sep 2020 → Mar 2025 acute myeloid leukemia, FLT3 internal tandem duplication Astellas Pharma Global Development, Inc.
Terminated
No outcome recorded
Phase 1/2
NCT04140487 Dec 2019 → Sep 2028 expected acute myeloid leukemia , chronic myelomonocytic leukemia M.D. Anderson Cancer Center
Recruiting
No outcome recorded
Phase 1/2
NCT03730012 Jun 2019 → May 2021 acute myeloid leukemia Astellas Pharma Global Development, Inc.
Completed
No outcome recorded
Phase 1/2
NCT03013998 Nov 2016 → Dec 2028 expected acute myeloid leukemia Beat AML, LLC
Recruiting
No outcome recorded
Phase 1/2
NCT02561455 May 2016 → Jul 2020 acute myeloid leukemia Astellas Pharma Global Development, Inc.
Completed
No outcome recorded
Phase 1/2
NCT02495233 Sep 2015 → Sep 2016 non-small cell lung carcinoma Astellas Pharma Global Development, Inc.
Terminated
No outcome recorded
Phase 1/2
NCT02310321 Feb 2015 → Aug 2021 acute myeloid leukemia Astellas Pharma Inc
Completed
No outcome recorded
Phase 1/2
NCT02014558 Oct 2013 → Aug 2017 acute myeloid leukemia Astellas Pharma Global Development, Inc.
Completed
No outcome recorded
Show 3 more trials Phase 2 12 trials
Phase 2
NCT07548710 May 2026 → May 2027 expected acute myeloid leukemia Ruijin Hospital
Recruiting
No outcome recorded
Phase 2
NCT07259707 Jan 2026 → Dec 2028 expected acute myeloid leukemia, FLT3 internal tandem duplication First Affiliated Hospital of Zhejiang University
Recruiting
No outcome recorded
Phase 2
NCT07032727 Sep 2025 → Jun 2027 expected —
M.D. Anderson Cancer Center
Recruiting
No outcome recorded
Phase 2
NCT06667973 Jun 2025 → Aug 2028 expected acute myeloid leukemia GIMEMA Foundation
Not yet recruiting
No outcome recorded
Phase 2
NCT06696183 Apr 2025 → Apr 2029 expected acute myeloid leukemia Technical University Dresden
Recruiting
No outcome recorded
Phase 2
NCT06317649 Sep 2024 → May 2029 expected acute myeloid leukemia National Cancer Institute (NCI)
Recruiting
No outcome recorded
Phase 2
NCT05564390 Jun 2024 → May 2029 expected acute myeloid leukemia with multilineage dysplasia , myelodysplastic syndrome , therapy related acute myeloid leukemia and myelodysplastic syndrome National Cancer Institute (NCI)
Recruiting
No outcome recorded
Phase 2
NCT06022003 Jan 2024 → Oct 2026 expected acute myeloid leukemia, FLT3 internal tandem duplication , acute myeloid leukemia, FLT3 tyrosine kinase domain point mutation French Innovative Leukemia Organisation
Recruiting
No outcome recorded
Phase 2
NCT06221683 Jan 2024 → Dec 2028 expected childhood acute myeloid leukemia Children's Hospital of Soochow University
Recruiting
No outcome recorded
Phase 2
NCT05199051 Jun 2023 → Jul 2028 expected acute myeloid leukemia Centre Antoine Lacassagne
Active not recruiting
No outcome recorded
Phase 2
NCT03836209 Dec 2019 → Oct 2023 overdue acute myeloid leukemia PrECOG, LLC.
Active not recruiting
No outcome recorded
Phase 2
NCT02927262 Jan 2017 → May 2021 acute myeloid leukemia, FLT3 internal tandem duplication Astellas Pharma Global Development, Inc.
Completed
No outcome recorded
Show 2 more trials Phase 2/3 1 trial
Phase 2/3
NCT07425808 Dec 2026 → Oct 2028 expected acute myeloid leukemia European Organisation for Research and Treatment of Cancer - EORTC
Not yet recruiting
No outcome recorded
Phase 3 9 trials
Phase 3
NCT07463651 May 2026 → May 2028 expected acute myeloid leukemia, FLT3 internal tandem duplication , disease related to hematopoietic stem cell transplant The First Affiliated Hospital of Soochow University
Recruiting
No outcome recorded
Phase 3
NCT07407140 Apr 2026 → Feb 2029 expected acute myeloid leukemia Institute of Hematology & Blood Diseases Hospital, China
Not yet recruiting
No outcome recorded
Phase 3
NCT06713837 Feb 2025 → Jan 2028 expected acute myeloid leukemia Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Recruiting
No outcome recorded
Phase 3
NCT04293562 Jul 2020 → Jun 2029 expected acute myeloid leukemia Children's Oncology Group
Recruiting
No outcome recorded
Phase 3
NCT04027309 Dec 2019 → Oct 2025 overdue acute myeloid leukemia , myelodysplastic syndrome with excess blasts-2 HOVON Foundation
Active not recruiting
No outcome recorded
Phase 3
NCT03182244 Oct 2017 → Dec 2023 overdue acute myeloid leukemia Astellas Pharma Inc
Active not recruiting
No outcome recorded
Phase 3
NCT02997202 Aug 2017 → Jan 2023 acute myeloid leukemia Astellas Pharma Global Development, Inc.
Completed
No outcome recorded
Phase 3
NCT02752035 Aug 2016 → Mar 2023 acute myeloid leukemia Astellas Pharma Global Development, Inc.
Completed
No outcome recorded
Phase 3
NCT02421939 Oct 2015 → Sep 2018 acute myeloid leukemia Astellas Pharma Global Development, Inc.
Completed
No outcome recorded
Phase not applicable 3 trials
— NCT06992934 Sep 2026 → Aug 2028 expected hematopoietic and lymphoid cell neoplasm Centre Hospitalier Universitaire de Nice
Not yet recruiting
No outcome recorded
— NCT07131059 May 2024 → May 2026 overdue acute myeloid leukemia Institute of Hematology & Blood Diseases Hospital, China
Recruiting
No outcome recorded
— NCT06265545 Feb 2024 → Jan 2026 overdue acute myeloid leukemia , refractory hematologic cancer Institute of Hematology & Blood Diseases Hospital, China
Recruiting
No outcome recorded
Phase not stated 3 trials
— NCT03409081 — acute myeloid leukemia Astellas Pharma Global Development, Inc.
No longer available
No outcome recorded
— NCT03315299 — acute myeloid leukemia Etan Orgel
No longer available
No outcome recorded
— NCT03070093 — acute myeloid leukemia Astellas Pharma Global Development, Inc.
Approved for marketing
No outcome recorded